News & Events

In orbit or on Earth, remote controlled therapeutic release

Houston Methodist Research Institute scientists will receive about $1.25 million from the Center for the Advancement of Science in Space to develop an implantable device that delivers therapeutic drugs at a rate guided by remote control. The device’s effectiveness will be tested aboard the International Space Station and on Earth’s surface. Austin-based NanoMedical Systems Inc. and the Houston Methodist Research Institute (HMRI) are also supporting the five-year project, bringing total funding to $1.92 million. The Center for the Advancement of Science in Space (CASIS) at Florida’s Kennedy Space Center announced new grants for Houston Methodist and two other institutions earlier today. “The prospect of developing and demonstrating a remotely controlled drug delivery …

Breast cancer may soon be diagnosed from a drop of blood

What could someday be the first blood test for the early detection of breast cancer was shown in preliminary studies to successfully identify the presence of breast cancer cells from serum biomarkers, say the Houston Methodist Research Institute scientists who are developing the technology. With a New York University Cancer Institute colleague, the researchers report in an upcoming Clinical Chemistry (now online) that the mixture of free-floating blood proteins created by the enzyme carboxypeptidase N accurately predicted the presence of early-stage breast cancer tissue in mice and in a small population of human patients. “In this paper we link the catalytic activity of carboxypeptidase N to tumor progression in clinical samples …